Cefalotin as antimicrobial prophylaxis in patients with known intraoperative anaphylaxis to cefazolin

Intraoperative anaphylaxis to latex.

This case report describes intraoperative anaphylaxis occurring in a fourteen-year-old female with spina bifida in which latex surgical gloves were incriminated as the aetiologic agent. The patient was non-atopic but since eight years of age she had developed localized angioedema and urticarial skin reactions on exposure to rubber. She had previously undergone several uneventful surgical proced...

Optimal dosage of cefmetazole for intraoperative antimicrobial prophylaxis in patients undergoing surgery for colorectal cancer

BACKGROUND Few studies have reported the dosage of cefmetazole (CMZ) for intraoperative antimicrobial prophylaxis in patients underwent surgery for colorectal cancer. We therefore examined the optimal intraoperative dosage of CMZ according to pharmacokinetic/pharmacodynamic (PK/PD) theory in patients who undergoing surgery for colorectal cancer. METHODS The study group comprised 23 patients w...

An Audit of Perioperative Antimicrobial Prophylaxis: Time to Take Action

Should Cefazolin Be the First-line Antimicrobial Prophylaxis Choice in Patients Undergoing Hysterectomy? A Systematic Review and Meta-analysis

Intraoperative anaphylaxis after intravenous atropine.

EDITOR: Although it is commonly used in clinical practice, there is not much awareness of the allergic potential of atropine since there are some reports of adverse reactions but rarely with clinical significance [1]. In the current literature on allergic reactions during anaesthesia, atropine appears in a very small number of patients, unlike the more frequent causative agents such as neuromus...